刚从监狱释放出来的Tom Joad （亨利·方达 Henry Fonda饰）回到俄克拉荷马的家的时候却发现原来的家里已经空无一人，打听之下才从农民Jim Casy（约翰·卡拉丁 John Carradine饰）口中得知，随着工业的发展，当地的农民们都被迫离开该地。Tom和Jim在Tom的叔父家里找到了Tom的家人，一家人决定到加利福尼亚去寻找新的工...
A pathologist, Dr. Warren Chapin (played by Vincent Price), discovers that the tingling of the spine in states of extreme fear is due to the growth of a "tingler"—a spinal parasite which can kill the host unless it is destroyed by screaming.
